15 results
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
following: • Fever ... rapidly, and empiric antibiotic ... agent are the main ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint ... Pain - Diagnostic ... acute rheumatic fever ... #Joint #Pain #MSK ... #rheumatology #
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... is the main clinical ... ALT ↑ bilirubin level ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Approach to Joint ... - Autoimmune Rheumatologic ... • Rheumatic fever ... #Diagnosis #MSK ... #rheumatology #
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... syndrome with acne: antibiotics ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management ... #Dermatology
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
B for initial management ... - Virtually never ... infections) - Main ... adverse effects = Hematologic ... #Pharmacology #Antibiotics
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... pain (especially ... responsive to antibiotics ... 9) Unexplained fever ... erythematosus #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... of the affected joint ... , and low back pain ... ) • HLA-B27 (to ... diagnosis #testing #Rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's lymphoma (HL ... • Dyspnea • Fever ... hemolytic anemia • Pain ... classification #hematology ... #oncology #management
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Diagnosis and Management ... deposition in joints ... attacks • Other joints ... swelling, significant pain ... #treatment #rheumatology