15 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
is the main clinical ... ALT ↑ bilirubin level ... Fibrin degradation products ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
B for initial management ... - Virtually never ... infections) - Main ... adverse effects = Hematologic ... #Pharmacology #Antibiotics
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... pain, dark urine ... Blood products contain ... #diagnosis #management ... #hematology #reactions
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
Blood Product Components ... Life Whole blood ... Hct 35%. 450mL blood ... Contents #Volume #Hematology ... #Management #Table
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Diagnosis and Management ... Pleuritic chest pain ... anemia • Sputum/Blood ... decubitus - air fluid level ... Lung Abscess Management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
pain, dark urine ... Blood products contain ... of transfused products ... #diagnosis #management ... #hematology #reactions
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
following: • Fever ... rapidly, and empiric antibiotic ... agent are the main ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... activated macrophages produce ... Self-limiting, chronic but stable ... anterior/posterior MSK ... Sarcoidosis #Diagnosis #Management
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint Pain ... acute rheumatic fever ... tumor • Non-bloody ... #Joint #Pain #MSK ... #rheumatology #
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- β-lactam antibiotics ... index < 2 • EPO Level ... result from low blood ... Anemia #oncology #hematology ... #diagnosis #management