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diagnosis liver differential lfts algorithm druginduced acute causes chemistry chronic cirrhosis elevation failure function functiontest gastroenterology hepatitis hepatocellular interpretation liverinjury
Drugs and Classes Associated with DILI and Type of Liver Injury #Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... and Type of Liver ... Injury #Medications ... #LiverInjury #Hepatology ... #Pharmacology #
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 Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... (>1000): • DILI ... injury) • Ischemic ... Differential #Diagnosis #hepatology ... #transaminitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) ... Guidelines ACLF ... Injury (DILI) ... EmoryGastroHep #ACLF ... Failure #Cirrhosis #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... involvement, Kidney injury ... duration), Several medications ... #Injury #Diagnosis ... #Algorithm #hepatology
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
abnormality vs bone Bili ... Hepatocellular injury ... 2: Cholestatic injury ... LFTs #Elevation #Transaminitis ... #diagnosis #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Failure (ALF): ... • Liver injury ... Hepatocellular Level ... #differential #Hepatology ... #transaminitis
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injury → liver ... , HSV, VZV • Medications ... #Diagnosis #hepatology ... #algorithm #Transaminitis
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