8 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Anticoagulant Sites of Action ... #Medications #Pharmacology ... #Pathophysiology ... #Mechanisms #DOAC ... #Hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
the only direct-acting ... = direct-acting ... molecular weight heparin ... Anticoagulation #Management #Hematology ... #Oncology
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
Summary table of ... the mechanism of action ... Molecular Weight Heparin ... anticoagulation #pharmacology ... #medications #doac
Lactulose: Mechanism of Action in Hepatic Encephalopathy
Lactulose → ↑ Lactic Acid, Acetic Acid → ↓ pH
: Mechanism of Action ... in Hepatic Encephalopathy ... #Lactulose #pharmacology ... mechanism #ammonia #hepatology ... #pathophysiology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... DOACs are substrates ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Medications - Heparin ... LMWH, warfarin, DOACs ... ) • Advanced Liver ... Deficiencies #Summary #table ... comparison #diagnosis #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... blood donor • Pathophysiology ... transfusion • Pathophysiology ... #hematology #diagnosis ... #comparison #table
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
Adrenoceptor Actions ... adrenergic #receptors #actions ... #pharmacology # ... pathophysiology ... #comparison #table