24 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Anticoagulant Sites of Action ... #Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
Lactulose: Mechanism of Action in Hepatic Encephalopathy
Lactulose → ↑ Lactic Acid, Acetic Acid → ↓ pH
: Mechanism of Action ... #Lactulose #pharmacology ... mechanism #ammonia #hepatology ... #pathophysiology
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
common direct-acting ... DAAs #Antivirals #table ... infectiousdisease #hepatology ... HepatitisC #Management #Pharmacology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... blood donor • Pathophysiology ... transfusion • Pathophysiology ... #hematology #diagnosis ... #comparison #table
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Appearance of Liver ... Lesions on Various ... #Lesions #Hepatic ... diagnosis #comparison #table ... #appearance #hepatology
Appearance of Liver Lesions on Computed Tomography (CT) - Arterial Phase, Portal Venous Phase and Delayed
Appearance of Liver ... Lesions on Computed ... #Lesions #Hepatic ... diagnosis #comparison #table ... #appearance #hepatology
Intern Pocket Cards - Pharmacologic Pain Management Options
Anti-inflammatory:
 • Acetaminophen (24 hours: < 3-4g in healthy
Pocket Cards - Pharmacologic ... Pain Management Options ... in CKD, <2g in liver ... Opioid #Conversion #Table ... #medications #pharmacology
Drugs Used for the Treatment of COVID-19 Infection

** Editor Note (from ophthalmology MD input) - Hydroxychloroquine/chloroquine
= mechanism of action ... clinical trial Ever ... Treatment #COVID19 #Pharmacology ... #Table #Management
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
#Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
Adrenoceptor Actions ... adrenergic #receptors #actions ... #pharmacology # ... pathophysiology ... #comparison #table