17 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... ascites), Chronic hepatitis ... • Autoimmune hepatitis ... Diagnosis #Algorithm #hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Trauma: Shock liver ... Budd-chiari syndrome, Portal ... • Iatrogenic: DILI ... Differential #Diagnosis #causes ... #hepatology
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
on hepatic ultrasound ... peripheral tracking of air ... ileus), intra-abdominal ... variety of other causes ... #hepatology #liver
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... • Iatrogenic: DILI ... Chronic viral hepatitis ... #injury #hepatitis ... diagnosis #algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... , vomiting, abdominal ... Antithrombin Ill • Ultrasound ... Diagnosis: Viral Hepatitis ... #Pregnancy #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Drugs • AIH ... • Alcoholic hepatitis ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... disease to acute liver ... upper limit of normal ... regarding need for treatment ... #Management #Hepatology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... >20) - Obtain abdominal ... exclude other causes ... HCV, DILI, HCC, ... Management #Algorithm #hepatology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
lung disease Caused ... disease - Portal ... older) on room air ... Treatment: • ... #hepatology
Portal Venous Gas on POCUS - Pneumatosis
Patient has ischemic bowel with portal venous gas.
Both cause intrahepatic
Both cause intrahepatic ... centrally located air ... result in small air ... POCUS #clinical #abdominal ... #ultrasound #Liver