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management hematology syndrome oncology cirrhosis hemophagocytic hepatopulmonary hlh liver lymphohistiocytosis aclf activation acute aflp anemia aplastic causes cell chronic classification
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... months without treatment ... Brain Failure Lung ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
rash) • Heart, lung ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... #Management #Hematology ... #Rheumatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
nausea, vomiting, abdominal ... Antithrombin Ill • Ultrasound ... ) Differential Diagnosis ... Maternal Support - Critical ... #Pregnancy #hepatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... effusion, Restrictive lung ... valve lesions Abdominal ... signs #symptoms #diagnosis ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... following: • Fever ... • Bicytopenia Treatment ... #management #treatment ... #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Emphysematous Cystitis Epidemiology: • Usually middle-aged diabetic women • Other RF: neurogenic bladder, urinary tract outlet obstruction,
immune compromise Clinical ... Abdominal or flank ... consider KUB or abdominal ... ultrasound as initial ... data • Early treatment
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
absence of intrinsic lung ... shunt (Type 2) Clinical ... on radioactive lung ... #management #treatment ... #hepatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Chronic lung ... lymphocytic interstitial lung ... Low serum IgG level ... hypogammaglobulinemia #immunology #hematology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... has five major clinical ... Pulmonary 3) Abdominal ... normal glucose level ... change in the lungs
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