10 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Diagnosis: >3 symptoms ... initiation • Differential ... #APML #diagnosis ... #management #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... - 80% have fever ... WBC >100k, + lab signs ... TLS #diagnosis #management ... #hematology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... anterior/posterior MSK ... : (distinct symptoms ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... /signs should be ... presence of metabolic syndrome ... Abnormal #Algorithm #Hepatology ... #Differential #
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... Diagnosis: HLH signs ... and symptoms can ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Myasthenic Crisis Checklist - Myasthenia Gravis

Evaluation 
 - Chest X-ray and lung ultrasound (exclude other lung
Phos), CBC with differential ... workup or TSH level ... if symptoms of ... monitoring (vital signs ... #CriticalCare
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
elevates the stress level ... for Refeeding Syndrome ... #diagnosis #differential ... #algorithm #management ... #treatment #criticalcare
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... decrease in HIV-1 RNA level ... #Inflammatory #Syndrome ... #Differential # ... Diagnosis #Management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... and/or symptoms ... defined sensory level ... Myelitis #diagnosis #management ... #neurology #differential
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome ... Presentation • Common Signs ... and Symptoms: ... #Hematology #HemeOnc