13 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase (ALP ... Diagnosis Algorithm ALP ... - Increased ALP ... disturbance (obstructed liver ... Highest • Bone • Liver
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... hepatocytes → Liver ... iMedEducation #AFLP ... #Fatty #Liver #
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
• CNS symptoms ... thin smear • Signs ... duplex or CTA • Liver ... Liver biopsy • ... node biopsy • Clinical
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... Hemolysis, Elevated Liver ... of Pregnancy (AFLP ... features: Liver ... diagnosis #icp #HELLP #AFLP
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Diagnosis Algorithm Symptoms ... quadrant discomfort Signs ... Elevated ALP 2. ... Liver biopsy findings ... Diagnosis #Algorithm #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... symptoms/signs ... ALP, alkaline phosphatase ... Abnormal #Algorithm #Hepatology ... #Differential #
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... synthesized in: liver ... Low phosphorus level ... mineralization Symptoms ... Hyophosphatasia #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
cholestasis → Cirrhosis/Liver ... and Symptoms: ... obstruction • ALP ... or higher • Liver ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... : INR/PT, aPTT(liver ... pylori test (GI symptoms ... bypass), LFT (liver ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Autoimmune diseases • Clinical ... the spleen or liver ... involvement Differential ... Malignancies (eg CML, ALL ... #hematology