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Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
, Sarcoidosis, GPA ... polychondritis, GPA ... - SLE Neurologic ... #joint #pain #differential ... #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
• Rheumatic fever ... Sarcoidosis • GPA ... Antiphospholipid-antibody syndrome ... Sarcoidosis #dermatology ... #skin #rashes #differential
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
of the joints (arthritis ... Episcleritis Signs ... lymphoma, breast CA ... - Hematologic ... #diagnosis #dermatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
arteritis (GCA) ... with systemic, neurologic ... Diagnosis = clinical ... systemic sx + signs ... very remarkable w/differential
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... reticularis Differential ... • Goodpasture syndrome ... • Giant cell arteritis ... #dermatology #rash
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... skin injury) • Neurologic ... (Clinical Dx). ... Behcet disease) Differential ... diagnosis #management #signs
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... purpura: Strong sign ... develop in pts with GCA ... affects the skin, neurologic ... cognitive impairment, neurologic
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... Coronary arteries - Fever ... • Cogan Syndrome ... purpura: strong sign ... #diagnosis #rheumatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
, rheumatoid arthritis ... life-threatening Differential ... test - Cogan sign ... - Peek sign ... diagnosis #management #neurology