20 results
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
Constitutional: Fever ... polyarthritis • Pulmonary ... exertion • Neurologic ... Sarcoidosis #Diagnosis #Symptoms ... #Signs #Pulmonary
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... if neutropenic fever ... Anemia #diagnosis #management ... #treatment #hematology
Cytomegalovirus (CMV) in HIV-AIDS Patients
Cytomegalovirus (CMV): double-stranded DNA virus, herpesvirus family.
CMV infection: virus isolation or detection
or signs. ... 50 or less: • Neurologic ... Pancreatitis • Pulmonary ... #differential #signs ... #symptoms
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
More Specific Signs ... Less Specific Signs ... Chest x-ray: signs ... acute HF → no signs ... #diagnosis #management
In order to better classify heart failure, the American College of Cardiology Foundation and the American
based solely on symptoms ... in patients who never ... show symptoms or ... signs of heart ... CHF #Congestive #HeartFailure
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... Pulmonary: dyspnea ... acute sarcoidosis Pulmonary ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... - 80% have fever ... WBC >100k, + lab signs ... TLS #diagnosis #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Diagnosis: HLH signs ... and symptoms can ... following: • Fever ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Actively maintained fever ... hyperthermia crisis (late sign ... amphetamines) Toxic: • Radiologic ... Phaeochromocytoma Neurologic ... Checklist #Diagnosis #Management
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... them, but urgent rheumatology ... GCA #Temporal #Signs ... #Management