13 results
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Disease: Primary ... Biliary Cirrhosis ... Cholangitis #pathophysiology ... #pbc #psc #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Hepatocellular - Liver ... Artery: Shock Liver ... Sophia_Hayes_MD #Liver ... Acute #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... intralobular bile ducts causes ... cholestasis → Cirrhosis/Liver ... Signs and Symptoms ... or higher • Liver
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
disturbance (obstructed liver ... Highest • Bone • Liver ... Intestine - Other causes ... biliary diseases ... Diagnosis #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... Extrahepatic - Biliary ... Choledocholithiasis, Biliary ... - Obstruction: Biliary ... diagnosis #algorithm #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... quadrant discomfort Signs ... of autoimmune disease ... Liver biopsy findings ... Diagnosis #Algorithm #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
sarcoidosis) • Liver ... metastasis • Fatty liver ... pregnancy • Primary biliary ... Veno-occlusive disease ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Cholestatic disease ... Duct Stone • Biliary ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... clinical symptoms/signs ... include extrahepatic biliary ... mellitus; USS, ultrasound ... Abnormal #Algorithm #Hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... DIC • Severe Liver ... Disease: - Impaired ... Treat primary cause ... Coagulation #diagnosis #causes