13 results
Hepatitis B Virus Serology and Interpretation
HBsAg - Anti-HBs - Anti-HBc - HBeAg - Anti-HBe
 - Acute
carrier state (low HBV ... DNA level) or HBeAg-negative ... DNA level) - ... Interpretation #diagnosis #laboratory ... #hepatology
Interpretation of Hepatitis B Serologies 
HBsAg - HBcAb (total) - HBcAb (IgM) - HBsAb
Susceptible to HBV
Immune
Interpretation of Hepatitis ... infection vs "Low level ... BrighamChiefs #HepatitisB ... serology #diagnosis #hepatology ... interpreation #testing #laboratory
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... HAV immunity; Liver ... Chronic Hepatitis ... Diagnosis #Management #Treatment ... #Hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... mg/dL) or acute liver ... failure #HepatitisB ... #HepBV #HBV #Treatment ... Indications #management #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... , HBV, HCV, HEV, ... ascites), Chronic hepatitis ... • Autoimmune hepatitis ... Diagnosis #Algorithm #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... normal - Infection (EBV ... #Patterns #Liver ... #Injury #hepatology ... #LFTs #transaminitis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... A/B/C/D/E, EBV, ... Differential #Diagnosis #hepatology ... Transaminitis #LFTs ... #hepatitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... Check Acute viral hepatitis ... serologies, HCV ... #differential #Hepatology ... transaminitis #LFTs
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... Lymphomas • Other hematologic ... #NonHodgkins #comparison ... #oncology #diagnosis ... #differential #hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... disease to acute liver ... Necrosis) If mild laboratory ... regarding need for treatment ... Diagnosis #Management #Hepatology