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diagnosis hematology management pain arthritis classification erythematosus gout leukemia lupus msk sle vasculitis workup acute approach autoimmune calcium causes cll
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
acute rheumatic fever ... • Chronic - Think ... hepatitis, herpes • Chronic ... #rheumatology # ... approach #workup #differential
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... Headaches, bone pain, fever ... , joint pain, bleeding ... #Leukemia #Hematology ... #Oncology #Diagnosis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis Differential ... - Autoimmune Rheumatologic ... • Rheumatic fever ... #pain #Differential ... Diagnosis #MSK #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... initiation • Differential ... Diagnosis: Infection ... #oncology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
Chronic CPP Crystal ... diagnose concomitant infection ... 12-24 Hours • Fever ... Diagnose concomitant infection ... Gout #Comparison #rheumatology
Acute and Chronic Causes of Dyspnea - Differential Diagnosis Pulmonary/Chest Wall: • Acute: Trauma, COPD exacerbation, Asthma
Causes of Dyspnea - Differential ... , Anaphylaxis, Infection ... poisoning, DKA, Fever ... Depression - VA Joint ... #Causes #Differential
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... Dermatomyositis Erythema chronicum ... • Rheumatic fever ... #skin #rashes #differential ... #diagnosis #rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Chronic CPP Crystal ... Resembles RA • Chronic ... diagnose concomitant infection ... Acute Pseudogout: Treatment ... Deposition #Disease #Rheumatology
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... the face (many differential ... search ANA and aPL ... , when infection ... erythematosus #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... weeks without infection ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
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