11 results
Proposed Treatment Algorithm for MAS / HLH

#MAS #HLH #Hemophagocytic #Lymphohistiocytosis #Management #Treatment #Algorithm #Hematology
Proposed Treatment ... Algorithm for MAS / HLH ... #MAS #HLH #Hemophagocytic ... Lymphohistiocytosis #Management ... #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... • Bicytopenia Treatment ... #Hemophagocytic ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
A subset of hemophagocytic ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... , ↓ Fibrinogen level ... #Hemophagocytic ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
Hemophagocytic Lymphohistiocytosis ... (HLH) Treatment ... #Hemophagocytic ... #Treatment #management ... #hematology
Severe Heart Failure & Cardiogenic Shock - Management Checklist 
Evaluation 
 - EKG & echocardiography
and/or digoxin level ... patients With chronic ... Revascularization, treatment ... #HeartFailure #Cardiology ... #Management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... Renal Failure Treatment ... APML #diagnosis #management ... #hematology #oncology
Portopulmonary Hypertension
Presence of pulmonary arterial hypertension in a patient with portal hypertension
No other obvious causes (chronic
obvious causes (chronic ... pressure < 15mmHg TREATMENT ... hemodynamics Liver ... Hypertension #diagnosis #management ... #hepatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's lymphoma (HL ... • Dyspnea • Fever ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Acute Recurrent Pericarditis
= recurrence of Acute Pericarditis (AP) after free interval >4-6 weeks without symptoms, >1/4
RED FLAGS: Fever ... Systemic symptoms: pulmonary ... Pericarditis #diagnosis #management ... #treatment #rheumatology ... #cardiology