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diagnosis differential hematology management algorithm acidosis activation agitation aplastic cardiology chronic classification delirium dermatology effusion elevatedmcv elevation fatigue fever hyperthermia
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Blood Smear • Drugs ... Myelodysplastic Syndromes ... Diagnosis #Algorithm #Causes ... #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... - Cytotoxic drugs ... index < 2 • EPO Level ... Treatment: ... #oncology #hematology
Fever vs Hyperthermia Fever: • Regulated in the hypothalamic thermoregulatory center • "Set point" raised by prostaglandin
: Drugs: Ecstasy ... Neuroleptic malignant syndrome ... ; Serotonin syndrome ... • Treatment: ... #Hyperthermia #comparison
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Renal Failure • Liver ... Hematologic • Anemia ... Myasthenia Gravis Pharmacologic ... Chronic Fatigue Syndrome
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
: - Drug induced ... - Hemolytic anemia ... Kasabach-Merritt syndrome ... • Drug reactions ... #rheumatology #
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Causes of Pericardial ... Non-Infectious: • Rheumatologic ... Mediterranean Fever ... • Metabolic: Uremia ... Dissection, Idiopathic, Drug-related
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... ) • Sepsis • Drug-induced ... with leukopenia, anemia ... Treatment: • Corticosteroids ... #Rheumatology
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... plasma insulin (treatment ... Conn's, Liddle's), Drugs ... , Heat stroke, Fever ... megaloblastic anemia
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
circulation If drugs ... before beginning treatment ... - Compartment syndrome ... 30mmHg) - Severe anemia ... Alcohol • Type B2: Drugs
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
treatment - Maternal ... neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... Megaloblastic anemia-rare ... #hematology
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