23 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
leakage of RBC's secondary ... - Hemolytic anemia ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #rheumatology #
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Classified among the secondary ... syndromes Clinical ... with leukopenia, anemia ... Treatment: • Corticosteroids ... #Rheumatology
Gynecomastia - Differential Diagnosis Algorithm
No Testicular Mass on Ultrasound
 • Adrenal Neoplasm
 • Increased Extraglomerular Aromatase
Aromatase Activity • Liver ... Klinefelter's Syndrome ... • Non-Tumor Secondary ... Diagnosis #Algorithm #causes ... #endocrinology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... index < 2 • EPO Level ... Treatment: ... #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... CausesAnemia ... factor (GCSF) treatments ... marrow studies Treatment ... #diagnosis #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... APS), Secondary ... CNS #neurology #rheumatology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... plasma insulin (treatment ... hyperaldosteronism, Secondary ... , Heat stroke, Fever ... megaloblastic anemia
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... to 8 years Clinical ... autoimmune hemolytic anemia ... Low serum IgG level ... DDX - Other causes
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
hypertension and/or drug treatment ... Chediak-Higashi syndrome ... drug reactions - Secondary ... Megaloblastic anemia-rare ... #hematology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... : • Clinical triad ... Type III Often Secondary ... classification #rheumatology