78 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
syndromes Clinical ... is the main clinical ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... #Rheumatology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Pathogenesis and clinical ... Anterior Cord Syndrome ... function below injury level ... • Central Cord Syndrome ... signs #symptoms #msk
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome ... Hypereosinophilic Syndrome ... • Clinically ... Diagnosis and Treatment ... #HES #Hematology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
levels, greater level ... anti-synthetase syndrome ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... organ damage • Treatment ... Low calcium • Treatment ... - Hyperkalemia treatment ... diagnosis #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... • Bicytopenia Treatment ... diagnosis #management #treatment ... #hematology
Mirizzi Syndrome on RUQ POCUS

Adult male-RUQ abd pain.VSS/Afeb. WBC-16.8K. Obstructive pattern on hepatic panel with normal
Mirizzi Syndrome ... with RUQ pain, fever ... #Liver #POCUS # ... Ultrasound #Gallstone ... #Clinical #Transverse
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... Presentation: • Fever ... index < 2 • EPO Level ... aplastic anemia Treatment ... Anemia #oncology #hematology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... Clinical Picture ... Diagnosis - Clinical ... Clinical DX: - ... immunologic assay - MuSK
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... triad: Fever, Arthralgia ... diagnosis #management #treatment ... #rheumatology