10 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... heart block • Sjogren ... Treatment: • ... diagnosis #rheumatology ... #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... , PRES Pathophysiology ... #rheumatology # ... cerebritis #diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: ... , macular, patchy ... dermatomyositis, Sjogren ... #Diagnosis #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... Systemic disease ... Arthritis, AS Treatment ... #management #signs ... #symptoms #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... overlaps with RA, SLE ... gland) biopsy • Ocular ... #Syndrome #Rheumatology ... #Diagnosis #Management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
VASCULITIS: • Behçet ... purpura: strong sign ... vasculitis, and SLE ... differential #diagnosis #rheumatology ... #classification
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Disease (CPPD) ... Pathophysiology ... Crowned Dens Syndrome ... #Disease #Rheumatology ... #diagnosis #management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
, such as SLE, atherosclerotic ... purpura: Strong sign ... ischemia • Skin: Erythematous ... vasculitis • Behcet ... Differential #Diagnosis #Rheumatology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
lupus erythematosus ... (SLE), Sjögren’ ... Hypoalbuminemia Treatment ... TAFRO #diagnosis #management ... #rheumatology #
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
chondritis • Ocular ... cases such as: • SLE ... Most common • Sjogren ... Sarcoidosis • Behcet ... Polychondritis #rheumatology