22 results
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Insufficiency Addison's ... Tuberculosis: can cause ... • Lymphoma Metastatic ... Symptoms: Reduced libido ... insufficiency #addisons
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
suspected: • Signs ... treatment • Elevated liver ... without discernable cause ... • Signs of osteoporosis ... hepatitis, T1DM, Addisons
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs ... in vitreous • Metastatic ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
hypotension - Nausea ... Amenorrhea, decreased libido ... Insufficiency #Signs ... Insufficiency #Addisons
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
significant portal HTN Signs ... obstruction) • Lack of signs ... sarcoidosis) • Liver ... metastasis • ... Fatty liver of pregnancy
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... Antithrombin Ill • Ultrasound ... diagnosis #management #pathophysiology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
hyalinization causes ... BRB breakdown causes ... #Retinopathy #pathophysiology ... #ophthalmology ... #diagnosis #signs
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
-> Leg Ulcers, Livedo ... inflammation tends to cause ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... circulation to veins -> Livedo ... Manifestations #pathophysiology ... #diagnosis #signs
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... cholestasis → Cirrhosis/Liver ... failure PBC Signs ... or higher • Liver