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diagnosis differential pulmonary dyspnea chronic management sob acute amiodarone boop cryptogenic effusion erythematosus hematology hepatology induced lung lupus organizing pneumonia
Causes of Chronic Dyspnea - Differential Diagnosis Algorithm Pericardial • Effusion • Cardiac Tamponade* • Constriction Myocardial •
Causes of Chronic ... Pericardial • Effusion ... • Asthma • COPD ... Interstitium • ILD ... Pulmonary - Other • Anemia
Cryptogenic Organizing Pneumonia (COP) Cryptogenic Organizing Pneumonia Overview: • Idiopathic form of organizing pneumonia • formerly BOOP
with CTD, drugs, malignancy ... Unknown • 6-7 cases ... Rare: pleural effusions ... , pleural thickening ... Pulmonary lymphoma, Diffuse
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Differential Diagnosis Algorithm ... Inflammatory: • IBD ... Damage: • Post-op ... Iron deficiency anemia
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Asthma - COPD ... • Parenchyma: ILD ... - Blood • Pleura ... : - Effusion ... Hematology: - Anemia
Causes of Pleural Effusion - Differential Diagnosis Algorithm Transudate - Hydrostatic • Congestive heart failure • Constrictive
Causes of Pleural ... Diagnosis Algorithm ... Noninfectious: • Malignancy ... • Asbestos • Uremia ... #Hepatology #causes
Acute and Chronic Causes of Dyspnea - Differential Diagnosis Pulmonary/Chest Wall: • Acute: Trauma, COPD exacerbation, Asthma
Acute and Chronic Causes ... Acute: Trauma, COPD ... Asthma attack, ILD ... flare, Pleural ... Tamponade • Chronic: Anemia
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Infections • Malignancy ... pneumonitis • Diffuse ... Serositis: • Pleural ... enteropathy, and diffuse ... lymphopenia, low PLT • Anemia
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
and exudative pleural ... • Patchy or diffuse ... embolism - Malignancy ... Exclusion of other ILDs ... LDH • ↑ ESR, CRP
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