99 results
Treatment of hyperkalemia via kaliuresis 
step 1 = volume resuscitation if hypovolemic
step 2 = consider fludrocortisone
step
Treatment of hyperkalemia ... determine response to diuretic ... #criticalcare #treatment ... #diuretics #diuresis ... #nephrology #algorithm
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Diuretics sites ... . mannitol) 3) Loop ... diuretic (e.g. ... Thiazides-type diuretics ... #pharmacology #nephrology
Flowchart to diuretic use in acute heart failure.

(A) Congestion with volume overload. 

(B) Treatment algorithm after
(B) Treatment algorithm ... Total loop diuretic ... maximal dose for IV loop ... following a single loop ... #CHF #Algorithm
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Pathophysiology - Diuretic ... Sites of Action Diuretics ... urearetics) 3) Loop ... Pathophysiology #Diuretics ... Sites #Action #nephrology
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... empagliflozin LOOP ... DIURETICS • Furosemide ... Tolvaptan #Diuretics ... summary #table #nephrology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Thiazides diuretics ... Metolazone Loop ... #Pharmacology #nephrology ... #conversion #loop
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
plasma insulin (treatment ... anhydrase inhibitors, loop ... syndrome (mimics loop ... diuretic use), ... differential #diagnosis #nephrology
Mechanism of Action of Diuretics
Amiloride, Triamterene, Spironolactone
Loop Diuretics
Thiazides
Acetazolamide

#Diuretics #Mechanism #Action #pharmacology #pathophysiology #nephrology
Mechanism of Action of Diuretics ... Spironolactone Loop ... Diuretics Thiazides ... Acetazolamide #Diuretics ... pathophysiology #nephrology
Hypernatremia Classification and Features According to Volume Status
 - Hypervolemic hypernatremia - Cushing's syndrome, Primary hyperaldosteronism,
hypernatremia - Osmotic diuretic ... , Loop diuretics ... Postobstructive diuresis ... Comparison #Table #Nephrology
Hyponatremia Treatment Algorithm

CHF, Cirrhosis - Fluid restriction
SIADH - Fluid restriction
 - Consider salt tablets if etiology
Algorithm CHF ... consider adding loop ... diuretic Reset ... -> free water diuresis ... #Algorithm #Management