20 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... - Diuretic Sites ... urearetics) 3) Loop ... Adenosine #Nephron ... #Pathophysiology
Nephron Remodeling as a Mechanism of Diuretic Resistance. When high doses of loop diuretics are used
Nephron Remodeling ... a Mechanism of Diuretic ... high doses of loop ... diuretics are used ... #Pathophysiology
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... Remote use of loop ... or thiazide diuretics ... Vomiting/nasogastric suction ... pressure: Active diuretic
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
Acting on the Nephron ... - Diuretics and ... mannitol) 3) Loop ... spironolactone) #Pathophysiology ... #Nephrology #Nephron
Mechanisms of Loop Diuretic Action and Resistance. Panel A, loop diuretics circulate bound to protein. As
Mechanisms of Loop ... Diuretic Action ... Panel A, loop diuretics ... #Pathophysiology ... #Nephro #IM #LoopDiuretic
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Metolazone Loop ... loss through the nephron ... Pharmacology #nephrology #conversion ... #loop #thiazide
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Transcellular Shifts: - Alkalosis ... , nasogastric suction ... anhydrase inhibitors, loop ... diuretics, and ... syndrome (mimics loop
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... and their Functions ... acid and most diuretics ... limb of Henle's loop ... #Pathophysiology
Approach to Elevated Bicarbonate (HCO3)
Risk Factors for Hypercapnea? (Hx of COPD, OSA, sedative use, CNS/muscular disorders?)
(+)
Likely Metabolic Alkalosis ... Adenoma • Remote Diuretics ... - Loop or Thiazides ... - Loop or Thiazides ... #algorithm #diagnosis
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
Urine chloride < 20 mmol/l - Chloride responsive (Chloride
Causes of Metabolic Alkalosis ... Differential Diagnosis Algorithm ... Vomiting • NG suction ... fibrosis • Remote diuretic ... #Metabolic #Alkalosis