46 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... - Diuretic Sites ... urearetics) 3) Loop ... Adenosine #Nephron #Pathophysiology ... #Action #nephrology
Mechanism of Action of Diuretics
Amiloride, Triamterene, Spironolactone
Loop Diuretics
Thiazides
Acetazolamide

#Diuretics #Mechanism #Action #pharmacology #pathophysiology #nephrology
Mechanism of Action of Diuretics ... Spironolactone Loop ... Diuretics Thiazides ... #pharmacology #pathophysiology ... #nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... plasma insulin (treatment ... syndrome (mimics loop ... #Hypokalemia #Causes ... differential #diagnosis #nephrology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Metolazone Loop ... #Pharmacology #nephrology ... #conversion #loop ... #thiazide #classes
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
the Nephron - Diuretics ... mannitol) 3) Loop ... Diuretics (e.g. ... spironolactone) #Pathophysiology ... #Nephrology #Nephron
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Cyanide Toxicity Treatment ... Amyl nitrite - causes ... thiosulfate enhances conversion ... Toxicity #Toxicology #Pathophysiology ... #Management #Treatment
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Defining the cause ... Clinicians should also look ... Post-hypercapnia • Diuretics ... #nephrology #potassium
Causes of Hypomagnesemia
 • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
Causes of Hypomagnesemia ... Saline or osmotic diuresis ... disease • Drugs: Loop ... Hypomagnesemia #Causes ... differential #diagnosis #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... +2Cl- Symport (Loop ... Kidney stones caused ... Tolvaptan) • Treatment ... #Nephrology #Pharmacology
Diabetes – diabetic nephropathy
Majority of the literature in the area is applied to the diabetic nephropathy
Diabetes – diabetic ... applied to the diabetic ... be the primary cause ... - Cytokines #Pathophysiology ... #Nephrology #CKD