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diagnosis nephrology differential management causes metabolic algorithm diuresis hypokalemia pharmacology urinary balance cardiology criticalcare diuretics excretion fluid gitelman heartfailure hfref
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride • Cl- responsive metabolic alkalosis
Algorithm - Urinary Chloride ... Remote use of loop ... or thiazide diuretics ... , Congenital chloride ... blood pressure: Active
Mechanisms of Loop Diuretic Action and Resistance. Panel A, loop diuretics circulate bound to protein. As
Mechanisms of Loop ... Diuretic Action ... Panel A, loop diuretics ... compete with chloride ... #Pathophysiology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Metabolic Alkalosis ... Remote use of loop ... or thiazide diuretics ... blood pressure: Active ... diuretic use, Bartter
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
vomiting/ nasogastric suction ... • Thiazide or loop ... diuretics after ... renal tubule diuretic ... • Thiazide or loop
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Transcellular Shifts: - Alkalosis ... plasma insulin (treatment ... , nasogastric suction ... anhydrase inhibitors, loop ... syndrome (mimics loop
Diuresis in Critical Care - Achieving a Negative Fluid Balance Advantages Of A Negative Fluid Balance: •
Diuresis in Critical ... • Start with LOOP ... are short acting ... aldosterone states (CHF ... contraction metabolic alkalosis
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Diuretics and Agents ... • Metabolic alkalosis ... +2Cl- Symport (Loop ... the Nonspecific Cation ... Tolvaptan) • Treatment
Heart Failure (HFrEF) Treatment - GDMT for stage C For patients with Heart Failure with REDUCED
Failure (HFrEF) Treatment ... edema then add on loop ... diuretics. ... /ambcarerx #CHF ... Pharmacology #Management #Treatment
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Na delivery): CHF ... (IV loop diuretic ... acetazolamide) - IV loop ... Exchanges K+ for cations ... (10g PO tid) - caution
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
with thiazide diuretic ... Hypochloremic metabolic alkalosis ... Surreptitious diuretic ... Rhabdomyolysis Treatment ... nephrology #management #pathophysiology
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