11 results
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Remote use of loop ... or thiazide diuretics ... blood pressure: Active ... diuretic use, Bartter ... acidosis: Diabetic
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Remote use of loop ... or thiazide diuretics ... blood pressure: Active ... diuretic use, Bartter ... acidosisDiabetic
Mechanisms of Loop Diuretic Action and Resistance. Panel A, loop diuretics circulate bound to protein. As
Diuretic Action ... Panel A, loop diuretics ... shown in Panel C, diuretics ... step can mediate diuretic ... #Pathophysiology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Transcellular Shifts: - Alkalosis ... plasma insulin (treatment ... diuretics, and ... Renal tubular acidosis ... diuretic use),
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Ureterosigmoidostomy, jejunal loop ... , ileal loop ... Potassium-sparing diuretics ... loads (ammonium chloride ... #NonGap #Metabolic
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
vomiting/ nasogastric suction ... chronic respiratory acidosis ... diuretics after ... renal tubule diuretic ... diuretics actively
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... • Metabolic alkalosis ... +2Cl- Symport (Loop ... Diuretics) (Bumetanide ... Tolvaptan) • Treatment
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Causes of Metabolic Alkalosis ... Vomiting • NG suction ... tubular transport • Diuretics ... (loop/thiazide) ... MetabolicAlkalosis #NonGap
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
G-K), K-sparing diuretics ... improve GFR - Diuresis ... hypertonic Amp IVP • Diuretics ... (IV loop diuretic ... diuretic (lasix
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
with thiazide diuretic ... Surreptitious diuretic ... Renal tubular acidosis ... Rhabdomyolysis Treatment ... nephrology #management #pathophysiology