9 results
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Losses: - Diuretics ... diuretics, and ... thiazide-like diuretics ... #Causes #differential
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
with thiazide diuretic ... • Unexplained hypokalemia ... Surreptitious diuretic ... #management #pathophysiology ... #Hypokalemia
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Causes of High-anion ... Hypokalemia ... Hyperkalemia ... Drug-induced hyperkalemia ... Potassium-sparing diuretics
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Alkalosis - Differential ... tubular transport • Diuretics ... (loop/thiazide) ... deficiency #MetabolicAlkalosis ... #NonGap #Nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... Altitude sickness • Diuretic ... Diuretics; High-Ceiling ... Diuretics) (Bumetanide ... #Diuresis #Nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Decreased intake (rare cause in isolation)
GI loss - Urine loss
Causes of Hypokalemia ... diuretics / Bartter's ... syndrome • Thiazide diuretics ... Liddle's syndrome #Hypokalemia ... #Nephrology #Differential
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
G-K), K-sparing diuretics ... improve GFR - Diuresis ... hypertonic Amp IVP • Diuretics ... (IV loop diuretic ... diuretic (lasix
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
and Management ... Dermatomyositis) AKI - Pathophysiology ... Loop diuretics for ... Dialysis for severe hyperkalemia ... #Summary #causes
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
• LDH ↑ • Hyperkalemia ... Loop diuretics for ... Dialysis for severe hyperkalemia ... #causes #treatment ... #nephrology