40 results
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... empagliflozin LOOP ... DIURETICS • Furosemide ... Chlorthalidone POTASSIUM-SPARING ... #Pharmacology #summary
Mechanisms of Loop Diuretic Action and Resistance. Panel A, loop diuretics circulate bound to protein. As
Mechanisms of Loop ... Diuretic Action ... Panel A, loop diuretics ... binding to sodium–potassium–chloride ... #Pathophysiology
Flowchart to diuretic use in acute heart failure.

(A) Congestion with volume overload. 

(B) Treatment algorithm after
(B) Treatment algorithm ... Total loop diuretic ... maximal dose for IV loop ... following a single loop ... HeartFailure #Cardiology #Management
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
the Nephron - Diuretics ... mannitol) 3) Loop ... Diuretics (e.g. ... HCTZ) 5) Potassium-sparing ... spironolactone) #Pathophysiology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Metolazone Loop ... Piretanide Potassium ... Pharmacology #nephrology #conversion ... #loop #thiazide
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... Fluids Shift potassium ... renal function) - Loop ... diuretic (often ... #Hyperkalemia #management
Hyponatremia Treatment Algorithm

CHF, Cirrhosis - Fluid restriction
SIADH - Fluid restriction
 - Consider salt tablets if etiology
Hyponatremia Treatment ... consider adding loop ... diuretic Reset ... -> free water diuresis ... #Algorithm #Management
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... Summary Trauma ... Dermatomyositis) AKI - Pathophysiology ... Monitor potassium ... Loop diuretics for
Diuresis in Critical Care - Achieving a Negative Fluid Balance
Advantages Of A Negative Fluid Balance:
 •
Diuresis in Critical ... • Start with LOOP ... DIURETICS which ... ) to normalize Potassium ... Fluid #Balance #management
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Cyanide Toxicity Treatment ... thiosulfate enhances conversion ... Toxicity #Toxicology #Pathophysiology ... #Management #Treatment