28 results
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Anemia Intrinsic Causes ... : • Liver disease ... agents ex. lead, copper ... • Transfusion reactions ... classification #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... Other: Transfusion reaction ... , Copper and lead ... Extravascular #Causes ... differential #diagnosis #hematology
Wing-Beating Tremor of Wilson's Disease

Characterized by low frequency, high amplitude, near arm tremor caused by continuous
Tremor of Wilson's Disease ... Characterized by low ... near arm tremor caused ... #clinical #video ... #neurology #copper
Wing-Beating Tremor of Wilson's Disease

Characterized by low frequency, high amplitude, near arm tremor caused by continuous
Tremor of Wilson's Disease ... Characterized by low ... near arm tremor caused ... #clinical #video ... #neurology #copper
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... Presents as dyspnea ... Hypothermia: Due to low ... diagnosis #management #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... Rarely dominate the clinical ... manifest on the face, upper ... Polyangiitis #GPA #dermatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Causes purpura & ... TRALI): Leading cause ... Presents as dyspnea ... Hypothermia: Due to low ... diagnosis #management #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... Risk factors: Critical ... without other cause ... #hematology #diagnosis ... #comparison #table
Wing-Beating Tremor on Physical Exam

Seen in Wilson's disease, caused by copper toxicity (low ceruloplasmin)

#Wing #Beating #Tremor
, caused by copper ... toxicity (low ceruloplasmin ... #PhysicalExam #clinical ... #video #neurology ... #copper
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Diagnosis: • Low ... 300 mg/dL) • Low ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology