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Pathophysiology of hypotonic hyponatremia

by Helbert Rondon, MD @NephroMD

#hypotonic #hyponatremia #nephrology #algorithm #Pathophysiology
Pathophysiology ... of hypotonic hyponatremia ... #hyponatremia # ... nephrology #algorithm ... #Pathophysiology
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Modified Hyponatremia ... Algorithm Hypertonic ... Urologic irrigants Hypotonic ... Primary polydipsia, Low ... diagnosis #sodium #nephrology
Hypo-osmolar Hypotonic HypoNatremia Algorithm (Serum Na+ < 135 meq/L, serum Osm < 275 mosm/kg)
Assess Volume Status,
Hypo-osmolar Hypotonic ... HypoNatremia Algorithm ... Urine Osm #Hyponatremia ... Algorithm #Diagnosis #Nephrology ... #Differential #Hypotonic
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... water Extrarenal hypotonic ... salt intake: • Hypertonic ... administration #Hypernatremia ... Diagnosis #Causes #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Hyponatremia The ... can be high or low ... Primary polydipsia), Low ... differential #diagnosis #table ... #sodium #nephrology
Pathophysiology Based Approach to Hyponatremia - Diagnostic Algorithm

Not the "classic" Volume based approach. 

#Hyponatremia #Algorithm #Pathophysiology
Pathophysiology ... Based Approach to Hyponatremia ... #Hyponatremia #Algorithm ... #Pathophysiology ... #Differential #Nephrology
Hyponatremia with Severe Symptoms - Management Algorithm with Hypertonic Saline
The goal of acute management is to
Hyponatremia with ... Algorithm with Hypertonic ... probably not the low ... kidney_boy #Hyponatremia ... #Saline #nephrology
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
, Recent TURP Hypotonic ... Hyponatremia: ... Hypothyroidism Hypertonic ... diagnosis #causes #nephrology ... #sodium #low
True Hyponatremia Differential Algorithm

Instead (or in addition) of volume status examination, check urine sodium and serum
True Hyponatremia ... - Urine sodium low ... and uric acid low ... in euvolemic hyponatremia ... Algorithm #Diagnosis #Nephrology
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Causes of Hypernatremia ... Diagnosis Algorithm Hypernatremia ... 300 mmol/kg • Hypertonic ... mannitol, glucosuria Low ... #Nephrology #Differential