23 results
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Differential Diagnosis ... and Gitelman syndrome ... #differential # ... diagnosis #causes #nephrology ... #magnesium #low
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Syndrome is a rare ... thiazide-sensitive sodium-chloride ... Hypermagnesuria, Hypomagnesemia ... #nephrology #diagnosis
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Hypomagnesemia - ... - Gitelman ... #Differential # ... Diagnosis #Low # ... Magnesium #Table
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Normal Acid-Base: Low ... , Gitelman syndrom ... #Hypokalemia #Differential ... #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Metabolic Alkalosis - Differential ... , NGT suction, Low ... , Gitelman Syndrome ... Metabolic #Alkalosis #Differential ... Diagnosis #Algorithm #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... thiazide-sensitive sodium ... alkalosis • Normal or low ... ratio 0.5%) Differential ... #nephrology #management
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
loop/thiazide) • Hypomagnesemia ... • Barrter's/Gitelman's ... Licorice • Liddle's Syndrome ... MetabolicAlkalosis #NonGap #Nephrology ... #Differential #
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Hypercalcemia, Hypermagnesemia ... Guillain-Barré syndrome ... Testing #Causes #differential ... #diagnosis #table ... #neurology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Metabolic Alkalosis - Differential ... , NGT suction, Low ... , Gitelman Syndrome ... Metabolic #Alkalosis #Differential ... Diagnosis #Algorithm #Nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
ascending limb Gitelman ... of epithelial sodium ... Defects #Kidney #Nephrology ... #Diagnosis #Differential ... #Table