11 results
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... • SPS - Sodium ... #pharmacology #table ... #comparison #nephrology
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Potassium #Binding #KBinders ... #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia ... #Nephrology #Agents
Phosphate Binders - Pros and Cons

Calcium carbonate (TumsTM) 
 - Most inexpensive, antacid properties useful for
Low pill burden. ... Low pill burden ... edgarvlermamd - Nephrology ... #Table #Comparison ... #Pharmacology #Nephrology
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Used Phosphate Binders ... Inexpensive - Treats hypocalcemia ... edgarvlermamd - Nephrology ... #Table #Comparison ... #Pharmacology #Nephrology
Algorithm for Management of Acute and Chronic Hyperkalemia
Acute Hyperkalemia:
 - IV calcium (10 mL of 10%)
Acute Hyperkalemia ... in 4 mL) - IV sodium ... - Consider K+ binders ... mL/min) - Oral sodium ... Chronic #treatment #nephrology
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
Saline (NS) - Comparison ... states such as acute ... Is Dangerous in Hyperkalemia ... decreased renal blood flow ... Normal #Saline #NS #comparison
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
: SIADH, Renal Sodium ... can be high or low ... Present (Uosm ≥100): Hypovolemia ... differential #diagnosis #table ... #sodium #nephrology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Pulm: Hypoxia, dyspnea ... - ACS, AKI, acute ... , Elevated Cr, Low ... hydration - Hyperkalemia ... Non calcium phos binders
Citrate Anticoagulation Toxicity

Hypernatremia (HyperNa):
 - Citrate solutions may have ↑ sodium content and should be paired
solutions may have ↑ sodium ... HypoMg): - Citrate binds ... circulation → ↓Mg Hypocalcemia ... dysfunction or low ... Toxicity #toxicology #nephrology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Acute Hemolytic ... Presents as dyspnea ... Citrate in RBCs binds ... Hypothermia: Due to low ... diagnosis #management #hematology