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management diagnosis hyperkalemia comparison pharmacology potassium algorithm anticoagulation chronic differential effects hematology high hyponatremia hypotonic kdigo lactated leukostasis lr lysis
Algorithm for Management of Acute and Chronic Hyperkalemia Acute Hyperkalemia: - IV calcium (10 mL of 10%)
Acute Hyperkalemia ... binders Chronic ... reinitiate and titrate ... #Chronic #treatment ... #nephrology
Potassium Binders for Management of Hyperkalemia • SPS - Sodium polystyrene sulfonate • Patiromer (veltassa) •
Potassium Binders ... • SPS - Sodium ... #treatment #pharmacology ... #table #comparison ... #nephrology
Characteristics of Commonly Used Phosphate Binders Aluminum - Potent and effective - Useful for
Inexpensive - Treats hypocalcemia ... burden Ferric citrate ... edgarvlermamd - Nephrology ... #Table #Comparison ... #Pharmacology #Nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Elimination (see Table ... acidosis) • Low ... Treatments: • ... Slow - don’t delay ... #potassium #nephrology
Citrate Anticoagulation Toxicity Hypernatremia (HyperNa): - Citrate solutions may have ↑ sodium content and should be paired
solutions may have ↑ sodium ... binds Mg: this ... circulation → ↓Mg Hypocalcemia ... dysfunction or low ... Toxicity #toxicology #nephrology
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
trial • Minimal K ... same line - Citrate ... states such as acute ... Is Dangerous in Hyperkalemia ... decreased renal blood flow
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
algorithm Urine Na+K ... can be high or low ... Present (Uosm ≥100): Hypovolemia ... differential #diagnosis #table ... #sodium #nephrology
KDIGO Treatment algorithm for management of acute hyperkalemia in the emergency department • Place on cardiac
KDIGO Treatment ... management of acute ... depletion • Consider K+ ... binder** • Consider ... potassium #high #nephrology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Pulm: Hypoxia, dyspnea ... - ACS, AKI, acute ... values: Elevated K, ... , Elevated Cr, Low ... Non calcium phos binders
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