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hyperkalemia management diagnosis comparison pharmacology algorithm binding differential acute agents anticoagulation causes chronic citrate gitelman high hyponatremia hypotonic k kbinders
Key Characteristics of Old and New Potassium-Binding Agents - Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd #Potassium #Binding #KBinders #Kayexelate
#Binding #KBinders ... #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia ... #Nephrology #Agents
Potassium Binders for Management of Hyperkalemia • SPS - Sodium polystyrene sulfonate • Patiromer (veltassa) •
Potassium Binders ... • SPS - Sodium ... treatment #pharmacology ... #table #comparison ... #nephrology
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... polystyrene sulfonate (Kayexelate ... nonspecifically binds ... of aspiration #Potassium ... #pharmacology #table
Hyperkalemia Treatment Options Stabilize cardiac membrane: • IV Calcium (peaks 5-10 minutes) Decrease potassium concentration: • IV Fluids Shift
Hyperkalemia Treatment ... 90 minutes) • Sodium ... minutes) • Stool - Kayexylate ... LouLectures #Hyperkalemia ... #nephrology
Characteristics of Commonly Used Phosphate Binders Aluminum - Potent and effective - Useful for
Used Phosphate Binders ... Inexpensive - Treats hypocalcemia ... edgarvlermamd - Nephrology ... #Table #Comparison ... #Pharmacology #Nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... alkalosis • Normal or low ... (renal potassium ... Rhabdomyolysis Treatment ... Syndrome #diagnosis #nephrology
Algorithm for Management of Acute and Chronic Hyperkalemia Acute Hyperkalemia: - IV calcium (10 mL of 10%)
in 4 mL) - IV sodium ... - Consider K+ binders ... mL/min) - Oral sodium ... Acute #Chronic #treatment ... #nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
: SIADH, Renal Sodium ... can be high or low ... Present (Uosm ≥100): Hypovolemia ... differential #diagnosis #table ... #sodium #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Elimination (see Table ... acidosis) • Low ... Redistribution Treatments ... Slow - don’t delay ... #potassium #nephrology
KDIGO Treatment algorithm for management of acute hyperkalemia in the emergency department • Place on cardiac
KDIGO Treatment ... management of acute hyperkalemia ... • Consider K+ binder ... #potassium #high ... #nephrology #KDIGO
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