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diagnosis differential management algorithm diuresis diuretics excretion framework gitelman hyperkalemia hypernatremia hypokalemia hyponatremia hypophosphatemia hypotonic k medications pathophysiology phosphate physiologic
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... mOsm/kg - Implies renal ... • Euvolemic (Low ... #Algorithm #nephrology ... #sodium
Workup for Hypophosphatemia - Differential Diagnosis Framework Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia Measure Urine Fractional Excretion
Workup for Hypophosphatemia ... Glucose, Acute resp. alkalosis ... FEPO4 ≥ 5% - Renal ... • Normal or Low ... #phosphate #nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
Sodium loss (diuretics ... can be high or low ... Primary polydipsia), Low ... differential #diagnosis #table ... #sodium #nephrology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Agents Regulating Renal ... • Metabolic alkalosis ... Excretion #Diuresis #Nephrology ... #Pharmacology # ... Medications #Table
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... • Normal or low ... • Hypokalemia (renal ... Syndrome #diagnosis #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
reabsorption) Workup ... 15 suggests ↓ renal ... Elimination (see Table ... acidosis) • Low ... Treatment #potassium #nephrology
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