19 results
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... mOsm/kg - Implies renal ... • Euvolemic (Low ... #Algorithm #nephrology ... #sodium
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Primary Metabolic Alkalosis ... Cl intake, Diuretics ... High Urine Cl-: Diuretics ... hyperaldosteronism • High PRA: Renal ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic Alkalosis ... Cl intake, Diuretics ... High Urine Cl-: Diuretics ... hyperaldosteronism • High PRA: Renal ... Diagnosis #Algorithm #Nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Sodium loss (diuretics ... can be high or low ... Primary polydipsia), Low ... differential #diagnosis #table ... #sodium #nephrology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Transcellular Shift: • Alkalosis ... Losses Non-renal ... vomiting) • Low ... • Discontinued diuretic ... Diagnosis #Algorithm #nephrology
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
Workup for Hypophosphatemia ... Glucose, Acute resp. alkalosis ... FEPO4 ≥ 5% - Renal ... Inh., Osmotic diuresis ... #phosphate #nephrology
Hypokalemia Differential Algorithm
Acidosis
 - RTA
 - Diarrhea
pH Normal 
 1. Decreased Mg 
 2. Intracellular Shift
Diuretics (discontinued ... Metabolic alkalosis ... Renal artery stenosis ... Diagnosis #Causes #Workup ... #Nephrology
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Diagnosis and Workup ... Repeat the sodium ... volume loss - diuretics ... Hypernatremia #Diagnosis #Workup ... #Algorithm #Nephrology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
• Increased renal ... blood flow • ... hypertrophy • Sodium ... activities • Diuretic ... pathophysiology #nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Causes of Metabolic Alkalosis ... Chloridorrhea Renal ... • Penicillins Renal ... tubular transport • Diuretics ... MetabolicAlkalosis #NonGap #Nephrology