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Initial Clinical and Laboratory Data Base for Defining Major Syndromes in Nephrology

#Major #Syndromes #Nephrology #Diagnosis #Workup
Defining Major Syndromes ... in Nephrology ... #Major #Syndromes ... #Workup #Differential ... #Table
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Osmolarity 3) Urine Sodium ... Uric Acid - Low ... Acid → renal salt wasting ... Diagnosis #Algorithm #nephrology ... #sodium #low #uricacid
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... • Euvolemic (Low ... , Cushing syndrome ... #Algorithm #nephrology ... #sodium
Workup of Hypercalcemia - Differential Diagnosis Algorithm
High or Normal PTH:
 • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Workup of Hypercalcemia ... Hypercalcemia Low ... PTHrP: - Low ... disease, Viral Syndromes ... #nephrology #PTH
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Cerebral salt wasting ... Hypothyroidism, Low ... Cirrhosis, Nephrotic syndrome ... algorithm #diagnosis #sodium ... #low #nephrology
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Familial renal Mg wasting ... syndromes ... Differential #Diagnosis #Low ... #Magnesium #Table ... Classification #Causes #Workup
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
pressure - Normal/low ... Serum albumin - Low ... edgarvlermamd - Nephrology ... Nephritic #Comparison #Table ... #Nephrology #Diagnosis
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
can be high or low ... Cerebral Salt Wasting ... Cirrhosis, Nephrotic syndrome ... differential #diagnosis #table ... #sodium #nephrology
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Cirrhosis, Nephrotic syndrome ... Cerebral salt wasting ... Primary polydipsia, Low ... Algorithm #diagnosis #sodium ... #nephrology
Hypocalcemia Workup - Differential Diagnosis Algorithm
 • Low Magnesium, High Magnesium - Functional Hypoparathyroidism
 • High
Hypocalcemia Workup ... Algorithm • Low ... metastases, Hungry bone syndrome ... #Hypocalcemia #Workup ... Diagnosis #Algorithm #nephrology