26 results
Pulmonary complications of targeted therapy
-Immune checkpoint inhibitors (e.g. pembrolizumab)
-Pneumonitis is uncommon (~5% of patients) but can
checkpoint inhibitors (e.g ... common presenting symptom ... case reports of pleural ... #Clinical #Diagnosis ... #Radiology #Honc
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
ARVs can have low ... • Depressive symptoms ... Diagnosis: MRI ... : The clinical ... Treatment: • HAART
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
intrinsic factor, IF) Clinical ... to manifest its symptoms ... previously dx'd associated ... , alcohol use, symptoms ... Check for IF ab Treatment
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
resonance imaging [MRI ... patients with clinically ... stimulation Clinical ... Multiple Sclerosis Treatment ... #treatment #MS
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Clinical ... Guillain-Barre Diagnosis ... axonal form • MRI ... GQ1b IgG Antibody associated ... #neurology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
conjunction with symptoms ... and treatment can ... skull neoplasms (e.g ... neuropathy (LHON) plus MRI ... lesions and clinical
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Dermatomyositis Clinical ... : • Triad of symptoms ... Heme associated ... #nephrology
Premature Ventricular Complexes (PVC's) - Summary Framework

Why PVCs?  Can be the first manifestation of cardiac
Digoxin toxicity Symptoms ... classified as: • Low ... 300 = NSVT EKG ... impulse • No associated ... more intensive treatment
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Group of disorders associated ... Clinical suspicion ... EKG, & restrictive ... • Persistent pleural ... enlargement • MRI
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Principles of HIV-Associated ... should be based on clinical ... Antimicrobial treatment ... Periventricular regions; associated ... Imaging: - MRI