12 results
Protease Inhibitors 

Protease Inhibitors are a class of commonly used antiretroviral medications for management of HIV.
Protease Inhibitors ... Protease Inhibitors ... Here's a broad overview ... cobicistat (3A4 INHIBITORS ... #Protease #Inhibitors
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
inducers (↑) and inhibitors ... concentrations, and inhibitors ... by inducers or inhibitors ... Pglycoprotein #inducers #inhibitors ... #Chemotherapy #Oncology
Amiodarone Toxicity and Monitoring

Tremor Ataxia 
Ocular neuritis 
Corneal Microdeposits 
Bradycardia 
Pulmonary fibrosis 
Hepatotoxicity 
Blue-gray skin
Amiodarone Toxicity ... Substrate CYP3A4 - Inhibitor ... #Amiodarone #Toxicity ... Adverse #Diagnosis #Management ... #Pharmacology
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Immune Checkpoint Inhibitor ... Toxicity Main ... CheckpointInhibitor #Toxicity ... Table #Diagnosis #Pharmacology ... #Oncology
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
Angiotensin-Converting Enzyme Inhibitors ... risk of digoxin toxicity ... increasing risk for toxicity ... Monoamine Oxidase Inhibitors ... supplementals #herbal #pharmacology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
CLL) - Summary Overview ... (Bruton kinase inhibitor ... Venetoclax (BCL2 inhibitor ... Lymphocytic #Leukemia #oncology ... hemeonc #diagnosis #management
Antiobesity Drugs and Their Effects
Orlistat
 • GI Lipase inhibitor
 • Reduces lipid absorption
 • Toxicity: Decreased
• GI Lipase inhibitor ... absorption • Toxicity ... incontinence • Toxicity ... #medications #pharmacology ... #management
Management of Immune Checkpoint Inhibitor (ICI) Induced Cardiotoxicity
Problem - Immune checkpoint inhibitors (ICIs) are associated with
Checkpoint Inhibitor ... Immune checkpoint inhibitors ... Severity Grading ... #Checkpoint #Inhibitor ... Cardiotoxicity #cardiology #oncology
Chloramphenicol - Antibiotics Class Overview

– 50S ribosomal inhibitor.   IV or PO (but PO form
Antibiotics Class Overview ... 50S ribosomal inhibitor ... due to potential toxicity ... #Pharmacology #Antibiotics ... #Review #Overview
Dupixent (dupilumab) for Asthma
Dupixent (dupilumab) is a biologic medication that is a dual inhibitor of IL4
that is a dual inhibitor ... injections as a loading ... dupilumab #Asthma #Management ... #Pharmacology