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hematology management blood cirrhosis differential product reactions abnormal aflp algorithm alp arterial biliary cholangitis coagulation common cvid dic disseminated embolism
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... synthesized in: liver ... Most cases diagnosed ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
ALP, alkaline phosphatase ... disease; AST, aspartate ... disease; T2DM, ... mellitus; USS, ultrasound ... Abnormal #Algorithm #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... PBC Labs: • Alkaline ... or higher • Liver ... #workup #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... Antithrombin Ill • Ultrasound ... ) Differential Diagnosis ... #Pregnancy #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential Diagnosis ... Myeloproliferative disease ... Syndrome, Ischemic Liver ... Venous #Arterial #pathophysiology ... #hematology #differential
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... to 8 years Clinical ... • Liver diseases ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... DIC • Severe Liver ... Disease: - Impaired ... #Coagulation #diagnosis ... #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... eruptions, diarrhea, liver ... Malaria, Borrellia (Lyme ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... eruptions, diarrhea, liver ... Malaria, Borrellia (Lyme ... #Transfusions #diagnosis ... #management #hematology
Hepatopulmonary Syndrome - Illness Script HPS is a pulmonary disorder of chronic liver disease characterized by a
abnormalities PATHOPHYSIOLOGY ... arteriovenous shunting causes ... of orthodeoxia CLINICAL ... digital clubbing DIAGNOSIS ... #hepatology
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