26 results
Granular & “Muddy Brown” Casts on Urine Microscopy
A. Finely granular cast B. slightly coarser granular cast
“Muddy Brown” Casts ... of mb granular casts ... appreciated at low ... Granular #MuddyBrown #Casts ... #Clinical #Nephrology
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
proteinuria, RBC casts ... → Refer to Nephrology ... for renal biopsy ... cystoscopy • Refer to Nephrology ... if cause not identified
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
• White cell casts ... • Hyaline casts ... disease • Granular casts ... key #diagnosis #nephrology ... #casts
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Hematuria: Red/Dark urine ... 1ml blood/liter urine ... hematuria: - RBC casts ... #urology #nephrology ... #renal #urine #
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... edgarvlermamd - Nephrology ... Microscopy #Diagnosis #Nephrology
Approach to Hypomagnesemia 

Fractional excretion of magnesium = (urine magnesium x serum creatinine)/ [0.7 (serum magnesium
of magnesium = (urine ... serum magnesium x urine ... differential #diagnosis #causes ... #nephrology #magnesium ... #low
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
require urgent nephrology ... : Hypovolemia, Low ... PROBLEM ~80% of AKI cases ... for WBCs, RBCs, casts ... workup #diagnosis #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Urine Cl-: Vomiting ... (late) • High Urine ... hyperaldosteronism • High PRA: Renal ... Diagnosis #Algorithm #Nephrology ... #Causes
Causes of Polyuria - Differential Diagnosis
Excess Intake of Water:
 • Primary polydipsia (a.k.a. "psychogenic polydipsia")
 •
Causes of Polyuria ... • Central Dl (Low ... Nephrogenic DI (Renal ... Polyuria Mimics (↑ urine ... #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
A urine K/Cr ratio ... suggests extra-renal ... causes • Laxative ... differential #potassium #nephrology ... #low