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oncology syndrome classification common cvid disorders dress eosinophil hes hodgkins hypereosinophilia hypogammaglobulinemia immunodeficiency immunology leukemia lymphoma mds monoclonal myelodysplasia myelodysplastic
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Screen for secondary ... causes of eosinophilia ... glucocorticoid treatment ... #Differential # ... diagnosis #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Secondary Causes ... Myeloproliferative HES - Lymphocytic ... #diagnosis #hematology ... #differential # ... management #eosinophils
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... , deficiency anemia ... #Diagnosis #Algorithm ... #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Reaction with Eosinophilia ... lymphadenopathy, eosinophilia ... Eosinophilia 4 ... DRESS #Syndrome #dermatology ... #diagnosis #management
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
Diagnosis Eosinophilic ... facei peripheral eosinophilia ... plasma cells, and eosinophils ... #Diagnosis #comparison ... #table #dermatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... anemia) • Systemic ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Coombs (-) hemolytic ... anemia due to cold ... Episodic angioedema+eosinophilia ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... • (Peripheral eosinophilia ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Diagnosis Algorithm ... frequently affected systems ... Better call hematology ... #Diagnosis #Algorithm ... #workup #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... Hodgkin Lymphoma Workup ... number of sites of disease ... classification #hematology ... #oncology #management
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