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diagnosis rheumatology differential management photo algorithm amyloid amyloidosis cd4 cryofibrinogenemia cvid dermatologic erythema gangrenosum genitals gpa granulomatosis hypogammaglobulinemia icl idiopathic
Erythema Multiforme: skin eruption secondary to allergic reaction from an antibiotic. Charlie Goldberg, M.D. - UCSD Catalog
Erythema Multiforme: skin ... eruption secondary ... #Dermatology #SkinRash ... Multiforme #Trunk #Back ... #Photo #UCSDH
Genital Skin Ulcers - Differential Diagnosis Algorithm Painful: • Herpes simplex • Haemophilus ducreyi (chancroid) • Behcet's
Genital Skin Ulcers ... ) • Behcet's syndrome ... Painless: • Primary ... genitals #Ulcers #ulcerative ... #skinrash #dermatology
Pyoderma Gangrenosum: Autoimmune disorder resulting in a vasculitis which causes slowly progressive ulceration of the skin.
vasculitis which causes ... progressive ulceration ... of the skin. ... #Photo #Dermatology ... #SkinRash #Pyoderma
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Bullae/Blisters • Ulceration ... • Goodpasture syndrome ... Polyangiitis #GPA #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
+ distinctive primary ... • Tumor lysis syndrome ... bone marrow and secondary ... CLL -> Invade Skin ... #Leukemia #Hematology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
NO underlying primary ... or secondary immune ... mL or 20% total lymphocyte ... ICL #diagnosis #hematology ... #Differential #Causes
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Primary (essential ... Diagnosis: • + Clinical ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
glands: • Focal lymphocytic ... other diseases • Secondary ... Hypocomplementemia • Can cause ... salivary ducts Clinical ... UIP, NSIP): • Lymphocytic
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... to 8 years Clinical ... Granulomatous lymphocytic ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Amyloidosis: • Primary ... dyscrasias • Secondary ... Clinical suspicion ... nephropathy is common ... Monoclonal B Cell Lymphocyte
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