14 results
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... of cancer-associated ... anticoagulants (DOACs ... #Anticoagulation ... #Management #Hematology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
thrombosis in cancer ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... #Anticoagulation ... #Management #Hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... ) Cancer-treatment ... DOACs are substrates ... Chemotherapy #Oncology #Hematology ... Interactions #Table #Pharmacology
Anticoagulant Bridging

 • Switching from LMWH
 • Switching from UFH
 • Switching from DOAC to Warfarin
Switching from DOAC ... from Warfarin to DOAC ... Anticoagulant #Bridging #anticoagulation ... #pharmacology # ... management #hematology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... anticoagulant treatment ... not available #DOAC ... anticoagulant #hematology ... #management #pharmacology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... microglobulin Treatment ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... workup #oncology #hematology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... immunosuppressive meds • +/- Anticoagulation ... #Treatment #management ... #pharmacology # ... rheumatology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
Over-anticoagulation ... #management #algorithm ... #pharmacology # ... treatment #medications ... decisionaid #cardiology #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... adsorption onto cancer ... vonWillebrand #Syndrome ... #treatment #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Lymphoma or other cancers ... gastric and breast cancer ... Granulomatous lymphocytic ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology