246 results
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
Large Granular Lymphocytic ... of autoimmune disease ... morphologic/clinical disease ... LargeGranular #Lymphocytic ... hemepath #pathology #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... minimal tumor burden Diagnosis ... Vmphocytosis on routine CBC ... chemotherapy for low-risk disease ... hematology #hemeonc #diagnosis
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Graves’ Disease: ... Findings B & T lymphocyte ... hyperplasia Note: B & T lymphocytes ... GravesDisease #pathophysiology ... symptoms #signs #diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... Lymphocytosis on CBC ... cells can indicate disease ... surface molecules: CD5 ... #Leukemia #diagnosis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... Leukemia (CBC with ... Lymphocytes) ... - Monoclonal Lymphocytes ... #Differential #Diagnosis
Pulmonary Infections in HIV-AIDS
Bacterial: 
 • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
Penicillium marneffei Parasitic ... : • CD4 < 200 ... Primary pulm HTN, Lymphocytic ... Infectious Diseases ... HIVAIDS #workup #diagnosis
Strongyloides fuelleborni Lifecycle
Free-Living Cycle
1) Eggs containing rhabditiform larvae passed in feces.
2) Rhabditiform larvae hatch in environment.
Parasitic Cycle ... become adults. 8) Parasitic ... intestine 9) Parasitic ... #diagnosis #pathophysiology ... infectiousdiseases #cdc
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
reaction - Atopic disease ... lymphomas, Hodgkin disease ... CD3-CD4+ T cells ... , IgG4-related disease ... #Differential #Diagnosis
Echinococcus Life Cycle
1) Adult in small intestine eggs
2) Embryonated egg in feces
3) Oncosphere hatches; penetrates intestinal
Echinococcus #LifeCycle #diagnosis ... #pathophysiology ... infectiousdiseases #cdc ... #parasite
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Toxoplasmosis (CD4 ... Chorioretinitis • Diagnosis ... CNS Lymphoma (CD4 ... • Nocardia • Parasitic ... #differential #diagnosis