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hematology oncology differential chronic classification cll leukemia workup biliary causes cholangitis cirrhosis common cvid diffuse disorders fungal hemeonc hodgkins hypogammaglobulinemia
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... morphologically mature B Lymphocytes ... rnature-appearing lymphocytes ... 500/uL clonal B lymphocytes ... #CLL #Chronic #Lymphocytic
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Algorithm Reactive ... • Chronic Lymphocytic ... Leukemia (CBC with ... Lymphocytes) ... - Monoclonal Lymphocytes
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Cancer affecting lymphocytes ... cell neoplasm • Lymphocytes ... Absolute blood lymphocyte ... #CLL #Chronic #Lymphocytic
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
prognosis • Nodular Lymphocyte ... cells absent, lymphocyte ... Mixed Cellularity, Lymphocyte ... Rich, Lymphocyte ... #Hematology #Diagnosis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... : • T lymphocyte ... but elevated as disease ... , IgG4 related disease ... #workup #hepatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... Granulomatous lymphocytic ... conditions Diagnosis ... and M panel Management ... #diagnosis #management
Neurosyphilis - Treponema pallidum - Diagnosis Algorithm Lumbar Puncture Indications: • Neuro / Ocular symptoms • HIV
Algorithm Lumbar ... • HIV (esp low CD4 ... Reactive VDRL 2) Lymphocytic ... #Algorithm #Lumbar ... #puncture #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
HL (MCHL) - Lymphocyte ... HL (LRHL) - Lymphocyte ... LDHL) - Nodular lymphocyte ... number of sites of disease ... #oncology #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
glands: • Focal lymphocytic ... Sjogren's Syndrome Diagnosis ... /aggregate) of CD4 ... UIP, NSIP): • Lymphocytic ... #Management
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
and Management ... incidentally via CBC ... • Treatment algorithms ... von Willebrand disease ... #treatment #hematology
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