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differential rheumatology dermatology management infections oncology primary signs symptoms systemic algorithm amebiasis causes cirrhosis generalized hepatology hiv leukemia lifecycle parasite
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... cells can indicate disease ... • Richter’s Syndrome ... #Leukemia #diagnosis ... workup #oncology #hematology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... Symptoms: - Lymphocyte ... Xeroderma (Dry skin ... #Pathophysiology ... #Diagnosis #Signs
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Generalized Differential Diagnosis ... Hyperthyroidism CBC ... Myelodisplastic syndrome ... Psychiatric Disease ... #generalized #dermatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
glands: • Focal lymphocytic ... /aggregate) of CD4 ... : • 10%-15% Pulmonary ... UIP, NSIP): • Lymphocytic ... , INC risk PE, Pulmonary
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
• Lymphocytic infiltration ... interstitial lung disease ... /pulmonary fibrosis ... RheumatoidArthritis #RA #pathophysiology ... signs #symptoms #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Criteria for Diagnosis ... Atypical Lymphocytes ... Skin involvement ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... : • T lymphocyte ... Examination: • Skin ... but elevated as disease ... #workup #hepatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... , breast CA - Hematologic ... Leukemia cutis Diagnosis ... - CBC may also ... #diagnosis #dermatology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Lady Windermere Syndrome ... : • Syndrome of ... Advanced HIV (CD4 ... Hematologic malignancy ... #infectiousdiseases
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