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causes chronic cll lymphocytic management algorithm bandemia diffuse erythematosus extravascular gap globulin hemeonc hemolysis hemolytic hodgkins intravascular lymphadenopathy mds monoclonal
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
• Systemic Lupus ... Leukemia (CBC with ... Lymphadenopathy #LAD ... #Causes #Hematology ... #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... • Neutropenia, anemia ... #Leukemia #diagnosis ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Vmphocytosis on routine CBC ... to large cell lymphoma ... chemotherapy for low-risk disease ... #Leukemia #oncology ... #hematology #hemeonc
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... - infiltrates (anemia ... Leukemia): • Lymphocytes ... #Leukemia #Hematology ... #Oncology #Diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... usually IgG) (e.g. lupus ... , CLL, lymphoma, ... Extravascular #Causes #differential ... #diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... titers > 1:80 • CBC ... and leukemia • ... #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Workup: • Full ... number of sites of disease ... Treatment • Early ... #diagnosis #classification ... #hematology #oncology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Tissue damage • Leukemia ... • Autoimmune diseases ... #differential # ... #WBC #CBC #hematology ... #pathophysiology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(-) hemolytic anemia ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... - Lupus - Leukemia ... - CBC may also ... #diagnosis #dermatology ... #oncology
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