37 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... cells can indicate disease ... #Leukemia #diagnosis ... workup #oncology #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... : • T lymphocyte ... failure PBC Signs ... bile ducts Differential ... #workup #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... Tyrosine Kinase activity ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Granulomatous lymphocytic ... interstitial lung ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... Diagnosis Portal ... >10 mmHg - clinically ... estrogen such as ... #hepatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... is also observed ... : HLH signs and ... #hematology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases Clinical ... Signs/Symptoms: ... /symptoms of active ... decreased reflexes Pathophysiology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Features: POEMS, AL ... capillary leak syndrome ... Ig deposition disease ... #Diagnosis #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
(HES) - Diagnosis ... and Management ... than 1500 and clinical ... Myeloproliferative HES - Lymphocytic ... #hematology #differential