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diagnosis msk hematology clinical differential video management oncology wrist algorithm sports tenosynovitis dequervains test chronic eichhoffs leukemia workup abnormal classification
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... 500/uL clonal B lymphocytes ... chemotherapy for low-risk disease ... - Progressive bore ... Leukemia #oncology #hematology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... predispose to other orthopedic ... Pain #SickleCell #Disease ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or on bone ... cells - Blood and Bone ... extramedullary disease ... -> AML: Blast crises ... #Leukemia #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... cells can indicate disease ... Warm AIHA • Bone ... lymphoma • Marginal zone ... workup #oncology #hematology
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
decades of life Causes ... resolve within one ... fever, fatigue, Nausea ... infiltration (lymphocytes ... Urticaria #diagnosis #rheumatology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
g/dl LLN B - Bony ... more: • Clonal bone ... Causes of false- ... amyloidosis Other causes ... MGUS #diagnosis #hematology
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm Tumours - See Bone Lesions Scheme Paget's Disease -
Tumours - See Bone ... Scheme Paget's Disease ... • Bone Marrow ... Diagnosis #Algorithm #Orthopedics ... #Causes
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Drug induced - Bone ... marrow disease ... deficiency • Liver disease ... Von Willebrand disease ... #rheumatology #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
PT, aPTT(liver disease ... bypass), LFT (liver disease ... candidate) - Bone ... patients if the cause ... #Workup #hematology
Vascular Joint Pain - Differential Diagnosis Algorithm - Constant Pain (Ischemia) - Acute Onset -
Peripheral Vascular Disease ... fractured long bone ... • Dislocated Bone ... Diagnosis #Algorithm #Orthopedics ... #Causes
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